Porcine reproductive and respiratory syndrome PRRS
The objective of this guide is to provide a practical summary regarding current knowledge and understanding of porcine reproductive and respiratory syndrome (PRRS).
LANGUAGE: ENGLISH
Authors: Ramírez, Alejandro
Release date: 2015
ISBN: 978-84-16315-20-8
Pages: 112
Binding: Hardcover. Spiral-bound
Dimensions: 11 x 20
The information presented is focused on clinically relevant and practical information to help field veterinarians and farm team personnel interested in animal health.
1. Introduction
Brief history
Agent
Structure
- Small
- Enveloped
- Shape
- Single strand RNA
- Nine open read fragments
- (ORFs 1a, 1b, 2, 2b, 3, 4, 5, 6, and 7)
2. Economic impact
Economic impact of PRRS
3. Clinical signs
Clinical signs of PRRS
- General clinical signs
- Reproductive clinical signs
- Respiratory clinical signs
4. Pathogenesis
Tissue tropism
Lesions
- Lung
- Lymph nodes
- Other lesions
5. Epidemiology
PRRSv epidemiologic characteristics
- Highly infectious
- Low transmission potential
- Incubation time
- Routes of transmission
- Persistent infections
- Mutations and quasispecies
- Subpopulations
6. Immunity
Introduction
Innate immunity
Definitions
Adaptive cell-mediated immunity
Humoral immunity
Maternal immunity
Cross-protection
7. Diagnostic tests
Agent detection
- Best samples
- Histopathology
- Virus isolation (VI)
- Polymerase chain reaction (PCR)
- Direct fluorescent antibody test (FA)
- Immunohistochemistry (IHC)
- Genetic sequencing
- Restriction fragment length polymorphism
- (RFLP)
Antibody detection
- Enzyme-linked immunosorbent assay (ELISA)
- Serum virus neutralization (SVN or SN)
- Indirect fluorescent antibody assay (IFA)
- Immunoperoxidase monolayer assay (IPMA)
8. Herd monitoring
Monitoring program design
- Serum
- Oral fluids
- Herd classification
- Important notes regarding breeding herd
- classification
9. Biosecurity
PRRSv resistance in the environment
- Environmental stability
- Water and manure
- Pork meat
- Vectors
Biosecurity practices
PADRAP
10. Control and elimination
Role of vaccines
- Killed vaccines
- Modified live virus (MLV) vaccines
Basics of control
- McRebel program
- Herd closure
- Homogenize
PrRsv elimination
- AASV position statement regarding PRRS
- Depopulation and repopulation (depop-repop)
- Test and removal
- Herd rollover
- Regional elimination
Expected Date: 05/08/2024
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